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Matthew D. Grimes

Matthew D. Grimes

🇺🇸 United States🏥 University of Wisconsin School of Medicine and Public HealthMD
Mentored by · fellowship 2018
Bradley A. Erickson

Training and career​

  • Current position Assistant professor (CHS) of urology, genitourinary reconstruction and male sexual health, University of Wisconsin School of Medicine and Public Health12
  • Medical school University of Washington School of Medicine12
  • Residency Urology, University of Wisconsin Hospitals and Clinics12
  • Fellowship Genitourinary reconstruction, University of Iowa Hospitals and Clinics (2018–2019), under fellowship director Bradley A. Erickson34
  • Research funding NIH K12 Urologic Research Career Development award (2020), for work on the molecular pathogenesis of lichen sclerosus urethral stricture disease5
  • TURNS Member, Trauma and Urologic Reconstructive Network of Surgeons6

Contributions​

Grimes studies the pathophysiology of urethral stricture disease and lichen sclerosus, including stricture histology and collagen structure, and reports ureteral reconstruction outcomes in radiated and non-radiated patients.789

  • Histopathology of anterior urethral strictures (2019). Led a blinded pathology review of 100 urethroplasty specimens: 21% had two or more lichen sclerosus features and 44% showed chronic inflammation, which was largely absent from isolated bulbomembranous strictures (9%); the 11% failure rate did not differ with inflammation.7 Cited on WARWIKI: Male Urethral Stricture.
  • Ureteral reconstruction after radiation (2022). In 47 consecutive single-surgeon ureteral reconstructions, radiated patients more often needed complex repairs (ileal ureter or autotransplantation; 35% vs. 7%), and success was 94% in radiated and 100% in non-radiated patients at a median follow-up of 30 months.8
  • Collagen in lichen sclerosus (2023). As senior author, showed greater collagen content and less homogeneous, more disorganized collagen structure in urethral, vulvar and foreskin tissue affected by lichen sclerosus than in unaffected tissue.9

Cited on WARWIKI

1 publication with Matthew D. Grimes as a listed author is cited on WARWIKI, ordered by the number of pages that cite them. Papers whose author list is shortened to "et al." before this name are not included.

  1. Grimes MD, Tesdahl BA, Schubbe M, et al. "Histopathology of Anterior Urethral Strictures: Toward a Better Understanding of Stricture Pathophysiology." J Urol. 2019;202(4):748–756. doi
    Cited on: Male Urethral Stricture

Footnotes​

  1. Matthew D. Grimes, MD. Department of Urology, University of Wisconsin–Madison. Accessed October 2026. ↩ ↩2 ↩3

  2. Matthew Grimes, MD. UW Health. Accessed October 2026. ↩ ↩2 ↩3

  3. Genitourinary Reconstruction Fellowship: People. University of Iowa Department of Urology. Accessed October 2026. ↩

  4. Genitourinary Reconstructive Surgery Fellowship curriculum. University of Iowa Hospitals and Clinics. Accessed October 2026. ↩

  5. Dr. Grimes receives NIH K12 Institutional Career Development award. Department of Urology, University of Wisconsin–Madison (August 4, 2020). Accessed October 2026. ↩

  6. Matthew D. Grimes, MD. Members, Trauma and Urologic Reconstructive Network of Surgeons. Roster: TURNS members. Accessed October 2026. ↩

  7. Grimes MD, Tesdahl BA, Schubbe M, Dahmoush L, Pearlman AM, Kreder KJ, Erickson BA. "Histopathology of anterior urethral strictures: toward a better understanding of stricture pathophysiology." J Urol. 2019;202(4):748–756. doi:10.1097/JU.0000000000000340 ↩ ↩2

  8. Grimes MD, Schubbe ME, Erickson BA. "A systematic approach for successful repair of radiated and non-radiated ureteral injuries." Transl Androl Urol. 2022;11(1):30–38. doi:10.21037/tau-21-574 ↩ ↩2

  9. Mora EMM, Champer MI, Huang W, Campagnola PJ, Grimes MD. "Collagen is more abundant and structurally altered in lichen sclerosus." Urology. 2023;173:192–197. doi:10.1016/j.urology.2022.11.036 ↩ ↩2