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Parastomal Hernia After Urinary Diversion

Parastomal hernia (PSH) is the most common long-term stomal complication after urinary diversion. After radical cystectomy with ileal conduit, 20–30% of patients develop a radiologic PSH within 2 years, ~31% of those become symptomatic, and roughly 15% require surgical repair.[1][2][3] Repair carries high recurrence rates (17–52%) regardless of technique and is complicated by the unique vulnerabilities of urinary stomas — UTI, mesh exposure to urine, conduit mesentery, and frequent concomitant ureteroenteric stricture or ventral hernia.[4][5][6][7]

This page is canonical for urinary-stoma PSH. Cross-linked from Continent Catheterizable Channels Principles — PSH also affects continent cutaneous channels (Indiana / Kock / Mitrofanoff) and is discussed below.


Epidemiology and Natural History

MetricValue
Radiologic PSH at 1 yr12–20%[1][2]
Radiologic PSH at 2 yr22–30%[1][2][3]
Radiologic PSH at 3 yr32%[1]
Pooled clinical incidence (systematic review)14.4%[4]
Symptomatic PSH (of those with radiologic PSH)31%[1]
Requiring surgical repair15–45% of symptomatic patients[1][5]
Median time to PSH development8–13 mo[1][3]
Risk plateauAfter year 3[1]

Approximately 26% of patients with radiologic PSH will progress (radiologic upgrading or need for surgery), with median time to progression of 12 months.[2]


Risk Factors

Risk factorEffect
Obesity / higher BMIOR 2.8 (BMI ≥30); HR 1.07 per unit BMI[1][2][3]
Fascial defect ≥24–30 mmOR 5.23 for defect ≥30 mm[4][5]
Female sexHR 1.86[1][5]
DiabetesHR 1.81[1]
COPDHR 1.78[1]
Prior laparotomyAdjusted HR 1.98[2]
Longer operative timeOR 1.25[4]
Lower postop eGFROR 2.17[4]
Poor nutritional status (NRI ≤83)AUC 0.731[5]
Postoperative UTIIndependent predictor[5]

No significant difference between open vs MIS cystectomy or intracorporeal vs extracorporeal conduit in most series.[8]


Why Urinary Stoma PSH Is Different

Urinary stoma PSH carries challenges fecal stoma PSH does not:[4][9][6][10]

  • Urinary complications dominate the postoperative course — ureteroenteric stricture, UTI, urine leak in up to 17–33%.
  • Conduit mesentery must be preserved during dissection, limiting mobilization and mesh-configuration options.
  • Concomitant ureteroenteric stricture may require simultaneous repair.[11]
  • Mesh-infection risk is heightened by constant exposure to urine — mesh extraction was needed in 8.6% in one ileal-conduit series.[6]
  • Neurogenic-bladder patients with continent catheterizable channels have weak abdominal-wall musculature.[9]
  • Stoma-appliance adherence is critical — a large hernia sac stretches overlying skin, often forcing resiting.[12][13]
  • Up to 50% of ileal conduit PSH are associated with a concomitant midline incisional hernia, requiring simultaneous repair.[8][5]

Conservative Management

Small, reducible, asymptomatic PSH:[12]

  • Hernia belt / support garment.
  • Stoma-appliance optimization (convex pouching, belt attachment).
  • Weight management and avoidance of heavy lifting.

Elective surgical repair is reserved for significant pouching difficulties, pain, recurrent obstruction, or incarceration.[12]


Prevention — Prophylactic Mesh at Index Surgery

The role of prophylactic mesh at the time of ileal conduit creation is controversial with conflicting RCTs.

StudyDesignMesh typePositionPSH (mesh)PSH (no mesh)Outcome
Liedberg 2020 (ISRCTN 95093825)[14]RCT, n = 242Lightweight syntheticSublay (retromuscular)11% clinical at 24 mo23%HR 0.45 (p = 0.02) — favors mesh
Djaladat 2024 (PUBMIC)[15]RCT, n = 146Biologic (FlexHD)Sublay intraperitoneal31% radiologic at 2 yr38%No significant difference
Donahue 2025 (MSKCC)[16]RCT, n = 178Semi-absorbable (Ultrapro)Sublay retromuscular47% radiologic at 24 mo33%No benefit; mesh arm trended worse

A network meta-analysis (25 studies across all stoma types) found prophylactic mesh significantly reduced PSH beyond 6 mo (OR 0.43, 95% CI 0.33–0.58), with the retromuscular approach lowest.[17] A Cochrane review concluded that mesh placement is safe and reduces PSH, especially with the open extraperitoneal (sublay) technique.[18]

The two most recent urology-specific RCTs (PUBMIC, MSKCC) failed to show benefit — leaving the evidence equivocal for ileal conduits specifically. The discrepancy may relate to mesh type (biologic and semi-absorbable performed worse than lightweight synthetic in the sublay position) and technique.[16][15][17]

A cost-effectiveness analysis found prophylactic mesh cost-effective ($2,115 / QALY gained), sensitive to mesh-infection probability.[19]

Novel stoma-construction technique

Tanaka et al. limit the fascial passage to ≤2.4 cm, create an oblique passage through the rectus, and separately fix the anterior and posterior rectus sheaths to the conduit. Radiologic PSH dropped from 19.6% to 3.5% (p = 0.011) without mesh.[20]


Indications for Surgical Repair

  • Symptomatic hernia: pain, pouching difficulties, cosmetic distress.
  • Recurrent bowel obstruction or incarceration / strangulation (emergency).
  • Difficulty with stoma-appliance adherence.
  • Concurrent need for other abdominal surgery.[12][13]

The ASCRS guidelines recommend mesh reinforcement for PSH repair (Grade 1C) — primary suture repair carries 46–78% recurrence vs ~20% with mesh.[13]


Mesh-Repair Techniques

TechniqueConfigurationRecurrence in ileal-conduit series
KeyholeMesh with aperture for the stoma limb35–52% — highest among mesh techniques.[4][13][6][21]
SugarbakerIntact mesh underlay; stoma exits laterally under mesh edge10–21.5% — generally lowest.[4][13][6][21]
SandwichTwo mesh sheets above and below fascia; stoma passes through13.5% in one prospective randomized study.[13]
3-D mesh implant (IPST)Purpose-made 3D alloplastic mesh via small open incision7.4% at median 29 mo (n = 40); 1 wound infection, no removals.[22]

The only RCT comparing Sugarbaker vs keyhole in the retromuscular position (Maskal, JAMA Surg 2024, n = 150) found no significant difference at 2 yr — Sugarbaker 17% vs keyhole 24% (adjusted RR 0.87, 95% CI 0.42–1.69). No difference in mesh-related complications, wound morbidity, QoL, or decision regret.[7]

Mesh position

PositionRecurrenceNotes
Preperitoneal6.5%Lowest in one large series[5]
Onlay25%Accessible but higher recurrence[5]
Intraperitoneal36.4%Most common in MIS repairs[5][2]
Retrorectus17–24% (RCT)Conflicting smaller-series data[5][7]

Mesh type

  • Permanent synthetic (polypropylene, polyester) — most commonly used; overall morbidity 24.9%, SSI 3.8%, mesh infection 1.7%.[13]
  • Biologic — recurrence ~15.7–18% at 3.8 yr; not superior to synthetic for elective repair.[13]
  • Synthetic resorbable — limited data; used in some prophylactic series.[23]

Open vs Minimally Invasive Repair

ParameterOpenLaparoscopic / Robotic
OR timeLongerShorter (p <0.001)[24]
Hospital stay6–7 d1–5 d (p <0.001)[24][25]
Wound complications18.6%Similar or lower[24]
SSIHigherRR 0.37–0.63 (p = 0.02–0.03)[24]
MortalityHigherRR 0.18 (p = 0.0009)[24]
Recurrence17–21%Similar (no significant difference)[24][25]

ASCRS allows MIS repair in selected patients (Grade 1C). Open is favored for larger defects and when stoma resiting is needed.[13] A 2025 meta-analysis confirmed laparoscopic repair shortens LOS by ~4 d, lowers SSI and mortality, with no difference in recurrence.[24]

Robotic-assisted repair

  • Xu 2021 — 4 patients robotic-assisted (3 Da Vinci SP). Median LOS 1 day, no intraoperative complications, no recurrences at median 18.3 mo. Concurrent ureteroenteric stricture repair, panniculectomy, and abdominal-wall reconstruction performed simultaneously.[11]
  • Dewulf 2022 — 15 patients, 10/15 robotic. Median LOS 5 d. One recurrence (6.7%) at d 66. One-third developed postop UTI.[10]

The robotic platform handles adhesiolysis in a hostile abdomen, allows simultaneous ureteroenteric stricture repair, and provides the dexterity needed for complex mesh placement around the conduit mesentery.[11][10]


Stoma Resiting vs In Situ Repair

Resiting has fallen out of favor because hernia recurs at the new site:[12][13][5]

  • Holland series — recurrence after resiting with mesh 34.8% vs 17.3% for in-situ mesh repair.[5]
  • All recurrences after resiting were at the new stoma site, independent of prophylactic mesh use.[5]

Resiting remains necessary when overlying skin is too damaged for appliance adherence or when body habitus has changed substantially.[13]

Laparoscopic stoma resiting for both continent channels and incontinent diversions has been described — channel dropped into the abdomen, hernia repaired with mesh, channel brought out through a laparoscopic port site. Continence and patency 100% at 2 yr.[9]


Continent Cutaneous Diversion PSH

PSH also complicates Indiana pouch, Kock pouch, and Mitrofanoff appendicovesicostomy:[9][26][27]

  • Helal 1997 (n = 21). 61.9% had simultaneous urinary incontinence — the hernia disrupts the continence mechanism. Repair: transabdominal takedown, hernia closure (Marlex if defect >6 cm), revision of the anti-incontinence segment, and stoma resiting. 89.5% success at 23.4 mo; incontinence corrected in 100% of affected patients.[26]
  • Stout 2021 — laparoscopic repair in 2 continent catheterizable channels and 2 incontinent diversions. 100% continence and patency at 2 yr.[9]
  • Mitrofanoff channels — PSH reported but uncommon (1/31 in one pediatric series). Small caliber of the appendiceal channel makes a smaller fascial defect.[27]

Key considerations for continent-diversion PSH: address the continence mechanism simultaneously (often disrupted by the hernia) and preserve the mesenteric blood supply to the catheterizable channel during dissection.[26][9]


Complications of PSH Repair

ComplicationIncidence
UTI17–33% (most common in ileal-conduit PSH repair)[4][10]
Wound complications18.6% (SSI, seroma, dehiscence)[24]
Mesh infection requiring removal1.7–8.6% (higher with urinary stomas)[6][13]
Stoma stenosis7.4%[5]
Bowel obstructionRare (mesh or adhesive)[6]
Recurrence17–52% by technique; keyhole highest[1][6][7]
Clavien ≥III7.8–12.9%[24][28]
90-day mortality0–6% (higher in elderly, open repair with resiting)[1][28]

Recurrent PSH

Recurrent PSH after initial repair is common and uniquely difficult:[6]

  • Roussel series — 22.9% of patients required reoperation for recurrence (30.7% keyhole, 18.2% Sugarbaker).
  • At reoperation, 50% could not receive synthetic mesh because of difficult adhesiolysis, leading to suture-only repair — which then required a third surgery in 37.5%.
  • Authors concluded that both keyhole and Sugarbaker may be inadequate for ileal-conduit PSH and that new approaches need to be explored.

Treatment Algorithm

  1. Asymptomatic / minimally symptomatic — conservative management with hernia belt and stoma-appliance optimization.[12]
  2. Symptomatic, small defect, no concomitant ventral hernia — MIS (laparoscopic or robotic) with Sugarbaker or sandwich; or 3-D mesh implant via small open incision.[13][24][11][22]
  3. Symptomatic, large defect, concomitant ventral hernia — open retromuscular repair with posterior component separation (transversus abdominis release) and mesh; Sugarbaker or keyhole — no clear superiority at 2 yr.[29][30][7]
  4. Stoma requiring resiting (skin damage, body-habitus change) — open or laparoscopic resiting with mesh reinforcement at new site; counsel re: high recurrence.[9][13][5][12]
  5. Concurrent ureteroenteric stricture — robotic approach allows simultaneous PSH repair and ureteroenteric reimplantation.[11]
  6. Continent diversion PSH — address continence mechanism simultaneously; consider stoma resiting with anti-incontinence revision.[26]
  7. Emergency (incarceration / strangulation) — emergent laparotomy with hernia reduction, bowel assessment, and repair.[12]

See Also


References

1. Hussein AA, Ahmed YE, May P, et al. Natural history and predictors of parastomal hernia after robot-assisted radical cystectomy and ileal conduit urinary diversion. J Urol. 2018;199(3):766–773. doi:10.1016/j.juro.2017.08.112

2. Ghoreifi A, Allgood E, Whang G, et al. Risk factors and natural history of parastomal hernia after radical cystectomy and ileal conduit. BJU Int. 2022;130(3):381–388. doi:10.1111/bju.15658

3. Liu NW, Hackney JT, Gellhaus PT, et al. Incidence and risk factors of parastomal hernia in patients undergoing radical cystectomy and ileal conduit diversion. J Urol. 2014;191(5):1313–1318. doi:10.1016/j.juro.2013.11.104

4. Cao R, Shao X, Li J. Management and outcomes profiles of parastomal hernia after radical cystectomy and ileal conduit urinary diversion: a systematic review. Hernia. 2025;29(1):180. doi:10.1007/s10029-025-03359-y

5. Holland AM, Lorenz WR, Mead BS, et al. Long-term outcomes after open parastomal hernia repair at a high-volume center. Surg Endosc. 2025;39(1):639–648. doi:10.1007/s00464-024-11375-9

6. Roussel E, Dupuis H, Grosjean J, Cornu JN, Khalil H. Initial and recurrent management of parastomal hernia after cystectomy and ileal conduit urinary diversion: a 10-year single-center experience. Hernia. 2024;29(1):57. doi:10.1007/s10029-024-03207-5

7. Maskal SM, Ellis RC, Fafaj A, et al. Open retromuscular Sugarbaker vs keyhole mesh placement for parastomal hernia repair: a randomized clinical trial. JAMA Surg. 2024;159(9):982–989. doi:10.1001/jamasurg.2024.1686

8. Su JS, Hoy NY, Fafaj A, et al. The European Hernia Society classification applied to the rare cases of parastomal hernia after ileal conduit urinary diversion: a retrospective cohort of 96 patients. Hernia. 2021;25(1):125–131. doi:10.1007/s10029-020-02230-6

9. Stout TE, Kasabwala K, Leslie DB, Elliott SP. A laparoscopic approach to parastomal hernia repair with re-siting of urinary stoma. Urology. 2021;152:199. doi:10.1016/j.urology.2021.01.020

10. Dewulf M, Pletinckx P, Nachtergaele F, et al. How-I-do-it: minimally invasive repair of ileal conduit parastomal hernias. Langenbecks Arch Surg. 2022;407(3):1291–1301. doi:10.1007/s00423-021-02393-5

11. Xu AJ, Shakir NA, Jun MS, Zhao LC. Robotic-assisted repair of post-ileal conduit parastomal hernia: technique and outcomes. Urology. 2021;158:232–236. doi:10.1016/j.urology.2021.08.030

12. Hedrick TL, Sherman A, Cohen-Mekelburg S, Gaidos JKJ. AGA Clinical Practice Update on management of ostomies: commentary. Clin Gastroenterol Hepatol. 2023;21(10):2473–2477. doi:10.1016/j.cgh.2023.04.035

13. Davis BR, Valente MA, Goldberg JE, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for ostomy surgery. Dis Colon Rectum. 2022;65(10):1173–1190. doi:10.1097/DCR.0000000000002498

14. Liedberg F, Kollberg P, Allerbo M, et al. Preventing parastomal hernia after ileal conduit by the use of a prophylactic mesh: a randomised study. Eur Urol. 2020;78(5):757–763. doi:10.1016/j.eururo.2020.07.033

15. Djaladat H, Ghoreifi A, Tejura T, et al. Prophylactic use of biologic mesh in ileal conduit (PUBMIC): a randomized clinical trial. J Urol. 2024;211(6):743–753. doi:10.1097/JU.0000000000003902

16. Donahue TF, Assel M, Cha EK, et al. Evaluating benefits of peristomal mesh placement at the time of radical cystectomy and ileal conduit formation: a phase 3 randomized controlled trial. J Urol. 2025. doi:10.1097/JU.0000000000004703

17. Hinojosa-Gonzalez DE, Saffati G, Kronstedt S, et al. Use of prophylactic mesh to prevent parastomal hernia formation: a systematic review, meta-analysis and network meta-analysis. Hernia. 2024;29(1):22. doi:10.1007/s10029-024-03219-1

18. Jones HG, Rees M, Aboumarzouk OM, et al. Prosthetic mesh placement for the prevention of parastomal herniation. Cochrane Database Syst Rev. 2018;7:CD008905. doi:10.1002/14651858.CD008905.pub3

19. Kanabolo DL, Park S. Prophylactic mesh placement with ileal conduit: a cost-effectiveness analysis. Urology. 2023;177:197–203. doi:10.1016/j.urology.2023.03.041

20. Tanaka T, Yamasaki K, Nofuji S, et al. Development and preliminary evaluation of a novel procedure for creation of an ileal conduit stoma aimed at preventing parastomal hernia. Int J Urol. 2024;31(5):512–518. doi:10.1111/iju.15394

21. Bel N, Blanc PY, Moszkowicz D, et al. Surgical management of parastomal hernia following radical cystectomy and ileal conduit: a French multi-institutional experience. Langenbecks Arch Surg. 2023;408(1):344. doi:10.1007/s00423-023-03062-5

22. Tully KH, Roghmann F, Pastor J, Noldus J, von Bodman C. Parastomal hernia repair with 3-D mesh implants after radical cystectomy and ileal conduit urinary diversion — a single-center experience using a purpose made alloplastic mesh implant. Urology. 2019;131:245–249. doi:10.1016/j.urology.2019.05.006

23. Tenzel PL, Williams ZF, McCarthy RA, Hope WW. Prophylactic mesh used in ileal conduit formation following radical cystectomy: a retrospective cohort. Hernia. 2018;22(5):781–784. doi:10.1007/s10029-018-1801-5

24. Abdelsamad A, Mohammed MK, Almoshantaf MB, et al. Minimally invasive versus open parastomal hernia repair: a comprehensive systematic review and meta-analysis. World J Surg. 2025. doi:10.1002/wjs.70013

25. Sarno G, Iacone B, Tedesco A, et al. End-colostomy parastomal hernia repair: a systematic review on laparoscopic and robotic approaches. Hernia. 2024;28(3):723–743. doi:10.1007/s10029-024-03026-8

26. Helal M, Austin P, Spyropoulos E, et al. Evaluation and management of parastomal hernia in association with continent urinary diversion. J Urol. 1997;157(5):1630–1632.

27. König A, Wiseman AX, Wildhaber B, Vidal I, Birraux J. Mitrofanoff procedure in children: use of the appendix and VQZ plasty seems to minimize complications. Pediatr Surg Int. 2025;41(1):304. doi:10.1007/s00383-025-06204-6

28. Howard R, Rob F, Thumma J, et al. Contemporary outcomes of elective parastomal hernia repair in older adults. JAMA Surg. 2023;158(4):394–402. doi:10.1001/jamasurg.2022.7978

29. Maskal SM, Ellis RC, Miller BT. Parastomal hernia repair, trying to optimize the impossible reconstruction. Hernia. 2024;28(3):931–936. doi:10.1007/s10029-024-03041-9

30. Raigani S, Criss CN, Petro CC, et al. Single-center experience with parastomal hernia repair using retromuscular mesh placement. J Gastrointest Surg. 2014;18(9):1673–1677. doi:10.1007/s11605-014-2575-4