Male Urethral Slings
Male urethral slings are minimally invasive devices used primarily for post-prostatectomy stress urinary incontinence (PPI), with overall success rates (cure + improvement) of 62–92% depending on sling design and incontinence severity.[1][2] Slings are a reasonable primary surgical option for mild-to-moderate male SUI; the artificial urinary sphincter (AUS) remains the gold standard for moderate-to-severe incontinence.[3]
Epidemiology and context
Post-prostatectomy incontinence affects 5–20% of men long-term after radical prostatectomy and is the most common indication for male sling surgery. Other causes include SUI after TURP, HoLEP, or pelvic radiation. Conservative management — pelvic floor muscle training and behavioral therapy — should be attempted for 6–12 months before surgical intervention.[1][3]
Classification of male slings
Male slings are broadly classified by mechanism of action and route of insertion.[2][4][5]
A. Fixed (non-adjustable) slings
- Retrourethral transobturator sling (AdVance / AdVance XP)
- Quadratic sling (Virtue)
- Bone-anchored sling (InVance) — largely historical
- Four-arm transobturator-prepubic slings (Surgimesh M-Sling)
B. Adjustable slings
- ATOMS (Adjustable Transobturator Male System)
- Argus / Argus T — adjustable retropubic / transobturator
- REMEEX — re-adjustable suburethral sling with suprapubic mechanical regulator
Mechanisms of action
Understanding the mechanism is critical for patient selection and counseling.
| Sling | Primary mechanism | Secondary mechanism |
|---|---|---|
| AdVance / AdVance XP | Repositioning of the lax membranous urethra proximally | Lengthening of the functional urethral length |
| Virtue (quadratic) | Ventral urethral elevation (transobturator arms) | Urethral compression against the genitourinary diaphragm (prepubic arms) |
| Bone-anchored (InVance) | Direct bulbar urethral compression | — |
| ATOMS | Adjustable bulbar urethral compression via inflatable cushion | — |
| Argus | Adjustable urethral compression via silicone foam pad | — |
A dynamic-MRI study demonstrated that the transobturator sling works by lengthening the vesicourethral anastomosis-to-bulbar-urethra distance, restoring functional urethral length toward continent post-prostatectomy controls. At rest, functional urethral length increased from 1.27 cm pre-sling to 1.53 cm post-sling, approaching the 1.92 cm seen in continent controls (P = .09).[6]
AdVance / AdVance XP — retrourethral transobturator sling
The most extensively studied male sling. The AdVance XP is the second-generation device with improved needle design and mesh anchoring.[9][10][11]
Technique
- Lithotomy position; perineal incision over the bulbar urethra
- Polypropylene tape passed retrourethrally through the transobturator route (inside-out or outside-in)
- The sling repositions the lax posterior urethra and membranous-sphincter complex proximally
- Non-compressive — does not obstruct voiding
- Operative time ~30–45 min; typically outpatient[9][12]
Patient selection — the "repositioning test"
- A positive repositioning test (improved coaptation of the membranous urethra with upward perineal pressure during cystoscopy) predicts success
- Requires residual sphincter function — patients with intrinsic sphincter deficiency or absent coaptive zone are poor candidates[13][14]
- Preoperative 24-hour pad weight <200–400 g and ≤2–3 pads/day favor success[13]
Outcomes
| Study | N | Follow-up | Cure | Cure + improved | Key finding |
|---|---|---|---|---|---|
| Bauer 2009[9] | 124 | 12 mo | 51.4% | 77.1% | Prospective; QoL significantly improved |
| Cornu 2009[12] | 102 | 13 mo (median) | 62.7% | 80.4% | Prior radiation predicted higher failure (P = .039) |
| Rehder 2012[17] | 156 | 3 yr | — | 76.8% | Stable efficacy at 3 yr; no worsening over time |
| Bauer 2017 (XP)[11] | 115 | 36 mo | 66.0% | 89.4% | Prospective multicenter; no erosions or explantations |
| Collado 2019[13] | 94 | 49 mo (median) | 77% | — | Preoperative pad weight predicts outcome |
| Chua 2019[15] | 215 | 56 mo (mean) | 44.7% | 69.8% | Largest long-term series; severity and urgency predict failure |
| Papachristos 2018[18] | 72 | 52 mo (median) | 51% (pad-free) | 76% | Trend of declining continence beyond 4 yr |
Key points
- Cure rates decline over time — from ~65–77% at 1 yr to ~45–62% at 4–5 yr, though most patients remain improved[15][16][18]
- Preoperative SUI severity is the strongest predictor of long-term success[15][16]
- No erosions or explantations in most large series — a major advantage over compressive slings[11][13]
Virtue quadratic sling
A unique four-arm design combining transobturator and prepubic fixation, providing both urethral relocation and compression.[7][19]
Technique
- Perineal incision; mesh placed beneath the bulbar urethra
- Two transobturator arms through the obturator foramen → urethral elevation
- Two prepubic arms anterior to the pubic bone → urethral compression
- Intraoperative retrograde leak point pressure (RLPP) confirms adequate urethral resistance
- The "fixation" technique (securing prepubic arms) significantly improved outcomes vs. the original unfixed design[7][19]
Outcomes
| Study | N | Follow-up | Cure | Improvement | Note |
|---|---|---|---|---|---|
| Comiter 2014 (fixation)[19] | — | 12 mo | — | 70.9% subjective / 79.2% objective | Fixation technique critical; 88.3% pad-weight reduction |
| Ferro 2017[21] | 29 | 36 mo | — | Significant improvement maintained | Effective for mild–moderate PPI |
| Roumeguère 2022[20] | 117 | 36 mo | 19% | 51% objective / 34% subjective | BMI, PVR, nocturia predict outcome |
Combines two mechanisms (relocation + compression) — theoretically greater urethral resistance than pure transobturator slings. No explantations required in the European multicenter study. Cure rates are lower than AdVance under strict definitions, but improvement rates are substantial.[20]
Bone-anchored sling (InVance) — largely historical
The first widely used male sling — silicone-coated polyester or polypropylene mesh secured to the inferior pubic rami with titanium bone screws.[2][22][23]
- Success rates 40–88% (highly variable across series)[2]
- Cure rates 39.5–87% depending on severity and sling material[22][23]
- Mesh infection 2–12% — the major limitation, usually requiring explantation[2]
- Silicone mesh outperformed porcine dermal collagen (87% vs. 56% cure)[22]
- Severe incontinence, prior radiation, or prior AUS substantially worsened outcomes[23]
- Largely abandoned due to high infection rates and superior alternatives[2]
ATOMS — Adjustable Transobturator Male System
A self-anchoring transobturator device with an adjustable cushion filled via a subcutaneous titanium port, allowing postoperative titration of urethral compression.[8][24][25][26][27]
Technique
- Perineal incision; mesh with integrated silicone cushion placed beneath the bulbar urethra
- Transobturator arms self-anchor to the inferior pubic ramus
- Subcutaneous titanium injection port placed over the symphysis pubis
- Postoperative saline injections through the port allow fine-tuning of urethral compression without reoperation
- Mean number of adjustments: 2.4–3.97[8][24]
Outcomes
| Study | N | Follow-up | Continence | Dry rate | Note |
|---|---|---|---|---|---|
| Seweryn 2012[8] | 38 | 16.9 mo | 84.2% | 60.5% | First prospective study |
| Hoda 2013[27] | 99 | 17.8 mo | 92% | 63% | European multicenter; 34.3% had prior failed surgery |
| Doiron 2019[24] | 160 | 9 mo (median) | 80.0% | — | Canadian multicenter; radiation → 62.5% vs 87.9% |
| Redmond 2021[26] | 289 | 19.6 mo | 73.3% | — | Largest series; radiation HR 2.3, diabetes HR 2.2 predict failure |
| Bajaj 2024[25] | 140 | 11 mo (median) | 82.9% | 76.4% | Effective across all severity levels |
| Téllez 2024[28] | 40 | 32.5 mo | 80% dry | 45% total continence | Effective after TURP / HoLEP, not just post-RP |
Advantages
- Postoperative adjustability — optimize continence without reoperation[8][24]
- Effective even in severe incontinence (36% severe SUI in the Canadian series)[24]
- Can be used after prior failed incontinence surgery (16–19% in large series)[24][26]
- No urethral erosion reported in most series[8][27]
Complications
- Explantation 4.4–7.9% (primarily port-related infection)[24][26]
- Perineal / scrotal pain transient in ~69%, resolving within 3–4 weeks[27]
- Port-related complications (infection, migration) 4–5%[24][26]
Adjustable retropubic slings — Argus, REMEEX
Suburethral pad connected to retropubic traction threads with a suprapubic mechanical regulator, allowing postoperative tension adjustment.[2][29]
- Success 61–79% at 26–45 mo follow-up[2][29]
- Erosion 3–13%, infection 3–11% — significantly higher than transobturator slings[2]
- Higher explantation rates than AdVance or ATOMS[2][5]
- Bowel perforation has been reported during implantation (2/18 in one series)[29]
- The re-adjustable feature is advantageous but comes with higher complication rates
Male sling vs. AUS — the MASTER trial
The MASTER trial is the only RCT comparing male sling (transobturator) to AUS — 380 men across 27 UK centers.[1][30]
- Primary outcome (continence at 12 mo): male sling noninferior to AUS (87.0% vs. 84.2% still incontinent by strict definition; risk difference 3.6%, 95% CI −11.6 to 4.6; non-inferiority P = .003)
- ICIQ-UI SF: both groups improved; AUS slightly greater improvement (mean difference 1.4, P = .02)
- Serious adverse events: fewer with sling (6 vs. 13)
- All secondary outcomes that showed statistically significant differences favored AUS
- Cost-effectiveness: sling more cost-effective (99% probability at £30,000 / QALY threshold), though slightly lower QALY gain[30]
- Conclusion: both procedures improve symptoms and satisfaction, but overall secondary analyses favor AUS[1]
A propensity-score-matched study confirmed that for moderate SUI (3–5 pads/day), AUS significantly outperformed the fixed transobturator sling: 94.3% vs. 68.6% continence at 12 mo (P <.001).[31]
A single-surgeon series demonstrated that for mild SUI, sling success was 78%; for moderate SUI, AUS achieved 80% vs. only 63% for sling (P = .02).[32]
Current consensus (6th ICI; AUA / SUFU)[3]
- Mild SUI (≤2 pads/day): male sling is an acceptable first-line surgical option
- Moderate SUI (3–5 pads/day): AUS preferred; sling may be offered with counseling about lower efficacy
- Severe SUI (>5 pads/day): AUS recommended; slings have poor outcomes in this group
Predictors of failure
| Risk factor | Effect on outcome | Strength of evidence |
|---|---|---|
| Prior pelvic radiation | OR 0.67–0.68 for success/cure; ~3× higher explantation and infection | Meta-analysis (strongest predictor)[34] |
| Severe preoperative SUI (≥5 pads/day) | Significantly lower cure and success rates | Multiple prospective studies[15][16] |
| Detrusor overactivity | Independent predictor of poor mid-term outcome | Prospective / urodynamic[35] |
| Obesity (BMI >30) | OR 7.9 for failure (AdVance); predictive in Virtue | Multiple series[14][20] |
| Prior bladder neck stenosis | OR 2.6 for failure | Prospective[14] |
| Weak residual sphincter / negative repositioning test | OR 29.0 for failure | Prospective[14] |
| Diabetes | HR 2.2 for failure (ATOMS) | Multicenter[26] |
| Prior incontinence surgery | Lower continence, improvement, satisfaction | Multiple series[3][26] |
Radiation is the single most important predictor of failure. A meta-analysis of irradiated vs. non-irradiated patients demonstrated significantly lower odds of success (OR 0.68, P <.001),[34] and single-institution experience with the AdVance sling specifically confirmed that radiation history materially worsens continence outcomes.[36]
Complications by sling type
| Complication | AdVance / XP | ATOMS | Bone-anchored | Argus / REMEEX | Virtue |
|---|---|---|---|---|---|
| Urinary retention (transient) | 12.9–15% | 2% | 5–12% | Variable | Rare |
| Perineal / scrotal pain | 3% chronic | 69% transient | Common early | Variable | 2.9% |
| Mesh infection | Very rare | 4–5% (port) | 2–12% | 3–11% | None reported |
| Urethral erosion | None reported | None reported | 1–3% | 3–13% | None reported |
| Explantation | Very rare | 4.4–7.9% | Common (infection) | Higher | None reported |
| De novo urgency / OAB | 16% | 10.3% | Variable | Variable | 10.3% |
| Bowel injury | Not reported | Not reported | Not reported | 2/18 (Argus) | Not reported |
References for the table: AdVance / XP[9][11][13][33]; ATOMS[24][26][27]; bone-anchored[2][22][23]; adjustable retropubic[2][29]; Virtue[19][20].
Sling after failed sling, and sling before AUS
A failed male sling does not preclude subsequent AUS implantation.[3] ATOMS can be used after prior failed incontinence surgery (16–19% of patients in large series).[24][26] Simultaneous male sling + penile prosthesis implantation is feasible and safe — social continence 72–100% and prosthesis satisfaction 84–100% in pooled series.[37]
Surgical technique — AdVance XP, step by step
- Patient in lithotomy; Foley catheter in place
- Perineal incision 3–4 cm over the bulbar urethra, midway between scrotum and anus
- Dissection through bulbospongiosus to expose the bulbar urethra
- Mobilize urethra from the central tendon posteriorly
- Helical trocar needles passed from the perineal incision through the obturator membrane to small groin incisions (inside-out)
- Polypropylene mesh tape attached to the needles and drawn through the transobturator path
- Mesh positioned retrourethrally behind the bulbar urethra, creating a hammock
- Tension applied to reposition the membranous urethra proximally — goal is relocation, not compression
- Mesh secured with non-absorbable sutures to bulbospongiosus — critical for long-term fixation; use of absorbable sutures with ≤4 stitches is an independent risk factor for failure (OR 8.4)[14]
- Cystoscopy to confirm no urethral injury and adequate coaptation
- Close perineal and groin incisions; Foley removed next day
- Operative time 30–45 min; typically same-day discharge[9][12]
Key takeaways
- Male slings are best suited for mild-to-moderate SUI (≤2–3 pads/day); for moderate-to-severe SUI, the AUS provides superior outcomes.[1][3][31][32]
- The AdVance XP is the most studied fixed sling with the best safety profile (no erosions, no explantations in most series), but cure rates decline over time (~45–62% at 5 yr).[11][15][18]
- ATOMS offers postoperative adjustability and can be effective even in severe SUI and after prior failed surgery, though port-related complications occur in ~5%.[24][25][26]
- Radiation history is the strongest predictor of sling failure across all types — irradiated patients have ~33% lower odds of success and ~3× higher odds of explantation.[34]
- The MASTER trial showed noninferiority of sling vs. AUS at 12 mo, but all secondary outcomes favored AUS. The sling is more cost-effective but provides slightly less QALY gain.[1][30]
- Residual sphincter function is essential for transobturator sling success — a positive repositioning test and adequate coaptive zone on cystoscopy are prerequisites.[13][14]
- Male slings do not preclude subsequent AUS placement, making them a reasonable first-line option in appropriate candidates.[3]
References
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37. Ammirati E, Polisini G, Giammò A. Surgical treatment options and outcomes for concomitant treatment of post-prostatectomy erectile dysfunction and male stress urinary incontinence: a systematic review of the literature. Int J Impot Res. 2026;38(3):193–205. doi:10.1038/s41443-025-01202-7